John E. Cole (born 4 August 1942 in Toronto, Ontario) was a Progressive Conservative party member of the Canadian House of Commons. He was an optometrist by career.
He represented the Ontario riding of York—Simcoe where he was elected in the 1988 federal election and served in the 34th Canadian Parliament. Cole left federal politics in the 1993 federal election after his defeat to Karen Kraft Sloan of the Liberal party.